Table I.
Patient characteristics.
| Variables | Control | SIRS | Sepsis | Severe sepsis | Septic shock | P-value |
|---|---|---|---|---|---|---|
| Number | 40 | 40 | 77 | 132 | 52 | |
| Age, years | 66.5 (26 to 82) | 65 (14 to 85) | 65 (20 to 93) | 69 (26 to 90) | 67 (23 to 94) | 0.602 |
| Male n (%) | 55.0 | 63.6 | 55.8 | 61.4 | 65.4 | 0.758 |
| Infection site (n) | ||||||
| Lung | 54 (70.1%) | 88 (66.7%) | 36 (69.2%) | 0.860 | ||
| Abdominal cavity | 3 (3.9%) | 6 (4.5%) | 4 (7.7%) | 0.650 | ||
| Urinary system | 1 (1.3%) | 7 (5.3%) | 2 (3.8%) | 0.430 | ||
| Gastrointestinal tract | 7 (9.1%) | 7 (5.3%) | 2 (3.8%) | 0.486 | ||
| Skin and soft tissue | 2 (2.6%) | 5 (3.8%) | 3 (5.8%) | 0.635 | ||
| Central system | 3 (3.9%) | 5 (3.8%) | 1 (1.9%) | 0.911 | ||
| Hepatobiliary system | 7 (9.1%) | 14 (10.6%) | 4 (7.7%) | 0.821 | ||
| Previous disease history n (%) | ||||||
| COPD | 12 (30.0%) | 27 (35.1%) | 51 (38.6%) | 16 (30.8%) | 0.658 | |
| Cardiovascular diseases | 13 (32.5%) | 29 (37.7%) | 53 (40.2%) | 17 (32.7%) | 0.659 | |
| Cerebrovascular diseases | 9 (22.5%) | 19 (24.7%) | 39 (29.6%) | 20 (38.4%) | 0.283 | |
| Diabetes | 11 (27.5%) | 27 (35.1%) | 49 (37.1%) | 21 (40.4%) | 0.617 | |
| Others | 4 (10.0%) | 12 (15.6%) | 25 (18.9%) | 10 (19.2%) | 0.564 | |
| 28-day mortality n (%) | 1 (2.5%) | 16 (20.8%) | 43 (32.6%) | 36 (69.2%) | <0.001 | |
| PCT (ng/l) | 0.05 (0.05–0.43) | 2.59 (0.41–5.09) | 3.97 (1.04–8.06) | 9.27 (6.84–13.30) | <0.001 | |
| MEDS score | 8.0 (5.5–10.5) | 9.0 (7.0–11.0) | 11.0 (8.0–14.0) | 14.5 (12.0–16.0) | <0.001 | |
| APACHE II score | 9.1±3.6 | 12.0±5.2 | 16.2±6.6 | 22.9±6.7 | <0.001 | |
| SOFA score | 2.0 (1.0–2.5) | 3.0 (2.0–6.0) | 7.5 (5.0–9.0) | 11.0 (10.0–14.0) | <0.001 | |
COPD, chronic obstructive pulmonary diseases; PCT, procalcitonin; MEDS, mortality in emergency department sepsis; APACHE II, acute physiology and chronic health evaluation; SOFA, sequential organ failure assessment.