Table II.
Levels of all biomarkers in each group.
| Items | Control | SIRS | Sepsis | Severe sepsis | Septic shock | P-value |
|---|---|---|---|---|---|---|
| Number | 40 | 40 | 77 | 132 | 52 | |
| Endocan | ||||||
| (ng/ml) | 32.53±9.13 | 47.31±6.11 | 52.86±5.17 | 54.99±5.28a | 58.25±4.08 | <0.001 |
| vWF (ng/l) | 1729.49±565.60 | 2736.22±436.98 | 3199.17±425.61 | 3909.27±334.02 | 4161.97±275.65 | <0.001 |
| ADAMTS-13 | ||||||
| (pg/ml) | 328.06±49.22 | 268.33±24.64 | 238.38±25.96 | 215.44±21.89 | 199.10±14.66 | <0.001 |
| vWF/ADAMTS1 | 5.43±2.06 | 10.32±2.14 | 13.59±2.40 | 18.34±2.54 | 21.01±2.01 | <0.001 |
Endocan, endothelial cell specific molecule-1; vWF, von Willebrand factor; ADAMTS-13, a disintegrin-like and metalloprotease with thrombospondin type 1 motif.
a
P<0.05 vs sepsis group.