The clinical significance of eight key genes in liver cancer. Gene expression levels between (A) patients <60 and ≤60 years old, (B) female and male, (C) tumor stages I–II and III–IV, and (D) tumor grades I–II and III–IV. Kaplan-Meier plots of (E) LSM4, (F) MFSD5, (G) HMGN1, (H) RTN2, (I) CDKN2AIPNL, (J) ITGA6, (K) ZCRB1 and (L) C1ORF54. HR, hazard ratio; LSM4, U6 snRNA-associated Sm-like protein LSm4; MFSD5, molybdate-anion transporter; HMGN1, non-histone chromosomal protein HMG-14; RTN2, reticulon-2; CDKN2AIPNL, CDKN2AIP N-terminal-like protein; ITGA6, integrin α-6; ZCRB1, zinc finger CCHC-type and RNA-binding motif-containing protein 1; C1orf54, uncharacterized protein C1orf54; TPM, transcripts per million kilobases. *P<0.05, **P<0.01 and ***P<0.001, indicating significant difference.