Table I.
Clinical information of all the tumor samples in the training set and the prescreening of the clinical factors significantly associated with prognosis.
| Univariables Cox | Multivariables Cox | ||||||
|---|---|---|---|---|---|---|---|
| Clinical characteristics | TCGA (n=415) | HR | 95% CI | P-value | HR | 95% CI | P-value |
| Age (years, mean ± SD) | 59.42±11.41 | 1.018 | 1.006–1.030 | 3.78×١٠−3a | 1.016 | 1.003–1.0301 | 1.73×10−2a |
| Neoplasm histologic grade (G1/G2/G3/G4/-) | 1/52/353/1/8 | 1.385 | 0.959–2.019 | 8.09×10−2 | – | – | – |
| Pathological stage (II/III/IV/-) | 23/327/62/3 | 1.375 | 1.037–1.823 | 2.74×10−2a | 1.001 | 0.730–1.3730 | 9.93×10−1 |
| Tumor recurrence (yes/no/-) | 220/171/24 | 1.316 | 1.057–2.012 | 6.08×10−9a | 1.385 | 1.272–1.544 | 6.76×10−8a |
| Neoplasm cancer status (tumor-free/with tumor/-) | 92/274/49 | 0.070 | 0.026–0.189 | 4.72×10−12a | 0.0481 | 0.017–0.133 | 5.61×10−9a |
| Lymphatic invasion (yes/no/-) | 103/55/257 | 1.144 | 0.704–1.859 | 5.87×10−1 | – | – | – |
| Venous invasion (yes/no/-) | 63/47/305 | 0.788 | 0.437–1.419 | 4.26×10−1 | – | – | – |
| Decreased (deceased/alive) | 121/139 | – | – | – | |||
| Overall survival time (months, mean ± SD) | 34.16±27.67 | – | – | – | |||
TCGA, The Cancer Genome Atlas; HR, hazard ratio; CI, confidence interval.
a
Significant P-value.