Table II.
ROC | ||||||||
---|---|---|---|---|---|---|---|---|
Datasets | C-index | Brier score | Log rank P-value | AUC | Sensitivity | Specificity | PPV | NPV |
Training set (TCGA, n=390) | 0.942 | 0.021 | 4.72×10−12a | 0.905 | 0.847 | 0.946 | 0.914 | 0.829 |
Validation set 1 (GSE25204, n=85) | 0.899 | 0.066 | 7.98×10−7a | 0.941 | 0.783 | 0.903 | 0.75 | 0.918 |
Validation set 2 (GSE27290, n=58) | 0.842 | 0.063 | 6.39×10−6a | 0.902 | 0.875 | 0.905 | 0.778 | 0.95 |
ROC, receiver operating characteristic; AUC, area under the receiver operating characteristic curve; PPV, positive prediction value; NPV, negative prediction value.
Significant P-value.