Figure 1.

Effect of yeast and/or paclitaxel on body weight change (g). Data are expressed as mean ± SE of 10 mice/group). ^aP<0.05 and ^AP<0.01, significantly different from the normal control untreated group. ^bP<0.05 and ^BP<0.01, significantly different from the control treated with yeast group. ^CP<0.01, significantly different from the EAC group. ^DP<0.01, significantly different from the yeast-treated EAC group. ^EP<0.01, significantly different from the paclitaxel-H-treated EAC group. ^FP<0.01, significantly different from the paclitaxel-L-treated EAC group. ^GP<0.01, significantly different from the yeast + paclitaxel-H-treated EAC group. Net final body weight = (final body weight - tumor weight). Body weight change = (net final body weight - initial body weight). EAC, Ehrlich ascites carcinoma. Groups: EAC, mice bearing tumors receiving intratumoral (i.t.) injections of PBS; Yeast, mice bearing tumors receiving i.t. injections of yeast (1×10⁷ cells/ml); paclitaxel-H, mice bearing tumors receiving paclitaxel at a high dose (10 mg/kg); paclitaxel-L, mice bearing tumors receiving paclitaxel at a low dose (2 mg/kg); Yeast + Paclitaxel-H, mice bearing tumors receiving yeast plus paclitaxel-H; Yeast + Paclitaxel-L, mice bearing tumors receiving yeast plus paclitaxel-L.