Table I.
Groups | Mean ± SE | % of change from EAC |
---|---|---|
EAC | 18.2±0.17 | – |
Yeast | 9.1±0.31a | 50 |
Paclitaxel-H | 10.9±0.09a | 40 |
Paclitaxel-L | 11.6±0.26a | 36 |
Yeast + Paclitaxel-H | 0.7±0.058a | 96 |
Yeast + Paclitaxel-L | 0.9±0.053a | 95 |
Data are expressed as mean ± SE of 5 mice/group.
P<0.01, significant difference compared to the untreated control group. EAC, Ehrlich ascites carcinoma. Groups: EAC, mice bearing tumors receiving intratumoral (i.t.) injections of PBS; Yeast, mice bearing tumors receiving i.t. injections of yeast (1×107 cells/ml); paclitaxel-H, mice bearing tumors receiving paclitaxel at a high dose (10 mg/kg); paclitaxel-L, mice bearing tumors receiving paclitaxel at a low dose (2 mg/kg); Yeast + Paclitaxel-H, mice bearing tumors receiving yeast plus paclitaxel-H; Yeast + Paclitaxel-L, mice bearing tumors receiving yeast plus paclitaxel-L.