Heart rate changes during anaesthesia. The differences between the two groups were statistically significant at T1, T2, T4 and T5. *P<0.05; **P<0.001 compared with saline group. T1, endotracheal intubation; T2, pneumoperitoneum; T3, extubation; T4, 1 min after extubation; T5, 5 min after extubation.