Table 5.

Investigations recommended for RSM by ESHRE

Basic investigations  Obstetric and family history, age, BMI, organic solvent, alcohol, mercury, lead, caffeine, hyperthermia, smoking  Full blood count (blood sugar level and thyroid function tests)  APLs (LAC, ACL)  Parental karyotyping (after 2 miscarriages)  Pelvic US and/or HSG and hysteroscopy and laparoscopy in the case of inconclusive findings Research investigations within the context of a trial  Fetoplacental karyotype studies  Testing for uterine and/or peripheral blood NK cells  Mannan-binding lectin level  Luteal phase, endometrial biopsy  Homocysteine/folic acid level  Thrombophilia screening

From Jauniaux et al. [3]. LAC = Lupus anticoagulant; US = ultrasound; HSG = hysterosalpingogram.