Table 2.

Significant genetic loci for blood pressure and hypertension reported in genome-wide association studies in Europeans (a) and Asians and Africans (b)

Chr	Strongest SNP	Position	EA	EAF	OR or BETA	p value	N	Closest gene	Trait	Ref.
a 1	Europeans rs1886773	1319056	A	0.03	−0.63	1.90E–10	233,789	NADK, CPSF3L	PP	[11]
1	rs14057	6623180	A	0.35	−0.3	2.50E–10	329,584	RNF207	SBP	[11]
1	rs9662255	9381890	A	0.43	−0.21	1.90E–10	310,618	chr1mb9	PP	[11]
1	rs880315	10736809	C	0.35	0.64	9.10E–16	133,125	CASZ1	SBP	[70]
1	rs17367504	11802721	G	0.15	−0.53	2.68E–18	149,714	MTHFR, NPPB	DBP	[70]
1	rs12744757	11846764	T	0.06	−0.7	7.54E–23	359,786	NPPA-AS1, NPPA	SBP	[70]
1	rs1042010	15467418	A	0.19	−0.41	3.03E–13	345,219	CELA2A	SBP	[70]
1	rs1048238	16015154	T	0.57	0.37	8.09E–07	140,299	HSPB7	SBP	[70]
1	rs6686889	24703979	T	0.25	0.19	3.60E–09	322,575	chr1mb25	DBP	[11]
1	rs871524	37945773	A	0.33	0.23	1.27E–11	304,987	INPP5B	PP	[70]
1	rs4360494	37990219	C	0.55	0.28	3.70E–16	282,851	SF3A3	PP	[11]
1	rs112557609	56111252	A	0.35	0.23	6.80E–12	325,952	RP4–710M16.1, PPAP2B	PP	[11]
1	rs3889199	59188070	A	0.71	0.35	1.80E–24	329,486	FGGY	PP	[11]
1	rs61767086	88600899	G	0.14	−0.41	1.90E–09	136,914	PKN2-AS1	PP	[70]
1	rs10922502	88894475	A	0.62	−0.38	2.20E–15	323,666	GTF2B	SBP	[11]
1	rs12129649	112688881	T	0.06	0.55	5.93E–19	343,172	MOV10	DBP	[70]
1	rs11466111	115286557	T	0.02	0.65	5.08E–10	319,490	chr1mb115	DBP	[11]
1	rs12405515	172388301	T	0.56	−0.17	1.40E–09	328,543	DNM3	DBP	[11]
1	rs12408022	217545447	T	0.26	0.2	2.40E–10	320,983	GPATCH2	DBP	[11]
1	rs10916082	227064925	A	0.73	−0.18	8.40E–09	327,636	CDC42BPA	DBP	[11]
1	rs2760061	228003374	A	0.47	0.23	2.10E–16	312,761	WNT3A	DBP	[11]
1	rs953492	243307890	A	0.46	0.22	7.40E–16	325,253	SDCCAG8	DBP	[11]
2	rs2289081	20682080	C	0.36	−0.22	5.50E–12	329,140	C2orf43	PP	[11]
2	rs55701159	24916727	T	0.89	0.29	7.20E–11	321,052	ADCY3	DBP	[11]
2	rs1275988	26691496	T	0.61	−0.58	2.35E–15	149,285	KCNK3	SBP	[70]
2	rs7562	28412873	T	0.52	0.26	1.90E–08	319,942	FOSL2	SBP	[11]
2	rs13420463	37290423	A	0.77	0.36	7.00E–11	330,307	PRKD3	SBP	[11]
2	rs4952611	40340603	T	0.58	−0.16	4.00E–08	309,395	SLC8A1	DBP	[11]
2	rs76326501	42940738	A	0.91	0.42	3.60E–18	318,127	AC016735.1	DBP	[11]
2	rs72876037	42967456	T	0.12	−0.53	1.65E–14	319,468	HAAO, ZFP36L2	SBP	[70]
2	rs11690961	46136197	A	0.88	0.34	3.90E–12	327,847	PRKCE	PP	[11]
2	rs74181299	65056838	T	0.62	0.23	9.60E–13	324,224	CEP68	PP	[11]
2	rs11689667	85264242	T	0.54	0.18	1.70E–08	330,634	TCF7L1	PP	[11]
2	rs2579519	96009418	T	0.63	−0.2	4.80E–12	311,557	GPAT2, FAHD2CP	DBP	[11]
2	rs62167177	145181135	T	0.14	−0.26	1.04E–09	289,338	TEX41	DBP	[11]
2	rs1446468	164106976	C	0.55	0.54	2.98E–13	141,331	FIGN, GRB14	SBP	[70]
2	rs79146658	178921341	T	0.91	−0.31	2.40E–10	321,318	CCDC141	DBP	[11]
2	rs13407401	179850979	A	0.29	−0.43	4.30E–08	145,919	ZNF385B	SBP	[70]
2	rs144073138	182410033	G	0.06	0.35	1.90E–08	295,411	PDE1A	DBP	[11]
2	rs7592578	190574865	T	0.19	−0.24	9.50E–12	304,672	TMEM194B	DBP	[11]
2	rs55780018	207661416	T	0.54	−0.39	5.90E–16	304,567	METTL21A, AC079767.3	SBP	[11]
2	rs1250259	215435759	A	0.74	−0.31	8.70E–19	325,485	FN1	PP	[11]
2	rs10932679	216787868	T	0.19	−0.23	1.70E–08	371,085	LOC101928278	PP	[70]
2	rs1063281	217804009	T	0.6	−0.2	1.30E–12	315,354	TNS1	DBP	[11]
3	rs142892876	1110752	T	0.001	10.69	5.00E–08	19,546	CNTN6	DBP	[71]
3	rs11716531	27415717	A	0.24	0.21	5.72E–14	373,386	SLC4A7	DBP	[70]
3	rs13082711	27496418	C	0.23	0.33	2.72E–10	146,340	SLC4A7	DBP	[70]
3	rs36022378	49876272	T	0.8	−0.2	4.70E–09	319,983	CAMKV, ACTBP13	DBP	[11]
3	rs743757	50438947	C	0.14	0.25	2.40E–10	328,836	CACNA2D2	DBP	[11]
3	rs9827472	56692618	T	0.37	−0.18	4.30E–10	323,058	FAM208A	DBP	[11]
3	rs9834975	122398816	T	0.44	0.15	1.14E–08	330,670	chr3mb122	DBP	[11]
3	rs62270945	128483046	T	0.03	0.61	1.80E–09	279,925	GATA2	PP	[11]
3	rs9859176	134281183	T	0.4	0.32	1.30E–11	322,428	RYK	SBP	[11]
3	rs143112823	154990178	A	0.09	−0.4	1.40E–14	297,343	RP11–439C8.2	DBP	[11]
3	rs419076	169383098	T	0.47	0.41	1.78E–13	193,725	MECOM	SBP	[9]
3	rs12374077	185599886	C	0.35	0.16	9.20E–09	327,513	SENP2	DBP	[11]
3	rs528908640	193644588	C	0.0005	14.67	2.00E–08	19,546	OPA1	DBP	[71]
3	rs9815354	41912651	A	0.17	0.4	7.12E–11	135,381	ULK4	DBP	[70]
4	rs871606	53933078	C	0.1	−0.5	1.53E–10	144,494	CHIC2	PP	[70]
4	rs17004869	80283879	T	0.05	0.72	1.02E–09	278,498	FGF5	SBP	[11]
4	rs2014912	85794517	C	0.85	−0.42	3.86E–10	143,933	ARHGAP24	PP	[70]
4	rs13107325	102267552	T	0.05	−0.68	2.28E–17	150,920	SLC39A8	DBP	[9]
4	rs13112725	105990585	C	0.77	0.41	3.11E–16	357,230	NPNT, TBCK	SBP	[70]
4	rs33966350	110510288	A	0.01	1.66	2.10E–11	216,630	ENPEP	SBP	[11]
4	rs66887589	119588124	T	0.52	−0.22	3.40E–15	324,397	PDE5A	DBP	[11]
4	rs78049276	147506351	C	0.13	0.27	1.04E–08	321,315	chr4mb148	PP	[11]
4	rs13139571	155724361	C	0.76	0.26	2.17E–10	185,393	GUCY1A3, GUCY1B3	DBP	[9]
4	rs1566497	168795997	A	0.42	0.24	1.90E–13	320,948	PALLD	PP	[11]
4	rs17059668	173663512	C	0.92	−0.33	2.80E–08	313,277	chr4mb174	PP	[11]
5	rs1173771	32814922	G	0.6	0.5	1.79E–16	158,664	C5orf23, NPR3	SBP	[9]
5	rs10078021	75742606	T	0.63	−0.16	1.30E–08	314,172	POC5	DBP	[11]
5	rs10057188	78541966	A	0.46	−0.21	6.70E–11	325,985	LHFPL2	PP	[11]
5	rs10059921	88218698	T	0.08	−0.53	4.00E–09	298,543	TMEM161B	SBP	[11]
5	rs337100	123210816	A	0.41	−0.28	4.61E–09	149,200	PRDM6 - SUMO1P5	PP	[70]
5	rs6595838	128532506	A	0.3	0.34	7.60E–12	328,401	FBN2	SBP	[11]
5	rs31864	158793185	A	0.55	0.21	5.50E–11	326,557	EBF1	PP	[11]
5	rs72812846	173950633	A	0.28	−0.21	2.20E–11	312,601	CPEB4	DBP	[11]
6	rs6911827	22130372	T	0.45	0.3	2.00E–10	326,471	CASC15	SBP	[11]
6	rs1800562	26092913	A	0.06	0.39	8.69E–17	373,770	HFE	DBP	[70]
6	rs151168737	31638615	A	0.46	0.25	3.60E–20	315,660	PRRC2A - BAG6	DBP	[70]
6	rs805303	31648589	G	0.61	0.38	1.49E–11	201,745	BAT2, BAT5	SBP	[9]
6	rs185819	32082290	C	0.51	0.37	1.04E–17	364,144	TNXB	SBP	[70]
6	rs78648104	50715296	T	0.92	−0.48	1.30E–08	305,426	TFAP2D	SBP	[11]
6	rs13205180	51967696	T	0.49	0.17	7.00E–10	325,419	PKHD1	DBP	[11]
6	rs9372498	118251323	A	0.08	0.33	1.80E–11	330,625	SLC35F1	DBP	[11]
6	rs11154027	121460244	T	0.47	0.21	1.10E–10	316,708	GJA1	PP	[11]
6	rs13209747	126794309	T	0.45	0.27	1.12E–09	146,105	RSPO3	DBP	[70]
6	rs17080102	150683634	C	0.07	−0.57	1.04E–10	147,869	PLEKHG1	DBP	[70]
6	rs36083386	152076778	I	0.11	0.44	1.50E–18	323,303	ESR1	PP	[11]
6	rs449789	159278093	C	0.14	0.36	2.40E–15	325,584	FNDC1	PP	[11]
6	rs147212971	165764963	T	0.06	−0.36	1.60E–09	296,010	PDE10A	DBP	[11]
6	rs1322639	169187008	A	0.78	0.32	4.80E–17	319,866	THBS2	PP	[11]
7	rs6461992	27181212	G	0.93	0.91	8.49E–24	311,598	HOXA3	SBP	[11]
7	rs1859168	27202740	C	0.92	0.44	1.85E–20	373,643	HOTTIP	DBP	[70]
7	rs76206723	40408372	A	0.1	−0.35	7.40E–12	328,162	SUGCT	PP	[11]
7	rs10260816	45970501	G	0.43	−0.3	5.31E–10	143,371	IGFBP3	PP	[70]
7	rs17477177	106771412	C	0.21	0.55	4.14E–22	149,296	PIK3CG	PP	[70]
7	rs13238550	131374297	A	0.4	0.33	1.90E–12	325,647	MKLN1	SBP	[11]
7	rs1011018	139763465	A	0.2	−0.33	1.50E–08	325,110	HIPK2	SBP	[11]
7	rs3918226	150993088	T	0.08	0.67	2.27E–13	118,604	NOS3	DBP	[70]
8	rs9693857	9409607	T	0.45	−0.34	2.40E–15	374,178	LOC105379231	SBP	[70]
8	rs1821002	10782555	G	0.6	−0.42	4.26E–19	323,712	BLK, GATA4	SBP	[11]
8	rs10107145	10900703	G	0.53	−0.36	1.44E–17	374,413	XKR6	SBP	[70]
8	rs6557876	26043159	T	0.25	−0.37	2.85E–14	369,457	EBF2	SBP	[70]
8	rs2978456	42467247	T	0.55	−0.19	1.20E–08	304,964	SLC20A2	PP	[11]
8	rs2978098	100664447	A	0.54	0.17	1.50E–09	324,424	SNX31	DBP	[11]
8	rs35783704	104954030	A	0.11	−0.41	7.08E–09	349,452	LRP12, ZFPM2	SBP	[70]
8	rs2071518	119423572	T	0.17	0.3	1.56E–08	149,046	NOV	PP	[10]
8	rs894344	134600502	A	0.6	−0.26	3.20E–08	329,834	ZFAT	SBP	[11]
8	rs4454254	140049929	A	0.63	−0.26	5.10E–16	330,022	TRAPPC9	PP	[11]
8	rs62524579	142979538	A	0.53	−0.18	3.80E–09	268,645	RP11–273G15.2	DBP	[11]
8	rs4076877	143820544	T	0.05	−0.42	3.57E–08	252,983	chr8mb144	DBP	[11]
9	rs872256	2496480	NA	NA	0.1	9.00E–09	8,423	SMARCA2, VLDLR	SBP	[72]
9	rs4364717	21801531	A	0.55	−0.18	1.30E–10	327,173	MTAP	DBP	[11]
9	rs568998724	107040156	A	0.0007	13.49	3.00E–08	19,546	LOC340512	DBP	[71]
9	rs72765298	125138717	T	0.87	−0.37	2.70E–14	316,271	SCAI	PP	[11]
10	rs9337951	30028144	A	0.34	0.28	2.50E–15	299,646	KIAA1462	PP	[11]
10	rs10826995	31793730	T	0.71	−0.21	1.10E–09	327,373	ARHGAP12, ZEB1	PP	[11]
10	rs4590817	61707795	G	0.83	−0.44	3.52E–13	146,522	C10orf107	MAP	[10]
10	rs932764	94136183	G	0.44	0.48	7.10E–16	160,885	PLCE1	SBP	[9]
10	rs112184198	100844757	A	0.1	−0.66	3.60E–18	323,791	PAX2	SBP	[11]
10	rs11191548	103086421	T	0.91	1.1	6.90E–26	161,709	NT5C2, CYP17A1	SBP	[9]
10	rs10787517	114055047	A	0.62	0.44	3.31E–18	272,852	ADRB1 - RNU6–709P	SBP	[70]
11	rs2649044	9742422	T	0.55	0.2	1.12E–14	343,652	SWAP70	DBP	[70]
11	rs7129220	10328991	G	0.89	−0.62	2.97E–12	182,871	ADM	SBP	[9]
11	rs177542	16901107	A	0.5	0.24	4.18E–08	143,257	PLEKHA7	DBP	[70]
11	rs11030119	27706555	A	0.31	−0.16	2.90E–08	330,002	BDNF	DBP	[11]
11	rs11442819	45186591	I	0.11	−0.28	7.10E–09	326,483	PRDM11	PP	[11]
11	rs751984	61510774	C	0.12	−0.41	1.98E–09	140,821	LRRC10B	DBP	[70]
11	rs4980532	63913247	T	0.56	0.3	1.53E–10	147,416	RCOR2	PP	[70]
11	rs67330701	69312240	T	0.09	−0.37	2.10E–12	276,760	MYEOV	DBP	[11]
11	rs2289125	89491285	A	0.21	−0.38	9.10E–22	307,682	NOX4	PP	[11]
11	rs633185	100722807	G	0.28	−0.56	1.21E–17	160,461	TMEM133, FLJ32810	SBP	[9]
11	rs8258	117412960	T	0.38	0.24	2.90E–13	327,038	CEP164	PP	[11]
11	rs11222084	130403335	T	0.35	0.35	2.26E–12	139,748	ADAMTS8	PP	[70]
12	rs10770612	20077705	A	0.8	0.31	6.90E–15	311,586	PDE3A	PP	[11]
12	rs73099903	53046995	T	0.07	0.51	1.95E–10	343,318	LOC283335	SBP	[70]
12	rs7312464	65980467	G	0.52	0.21	5.35E–10	289,978	chr12mb66	PP	[11]
12	rs17249754	89666809	A	0.16	−0.9	6.59E–20	146,304	ATP2B1	SBP	[70]
12	rs139236208	94486966	A	0.1	−0.36	1.60E–10	291,244	CCDC41	PP	[11]
12	rs3184504	111446804	T	0.47	0.45	3.59E–25	120,633	SH2B3	DBP	[9]
12	rs10850519	115490635	C	0.3	−0.21	5.10E–13	327,837	TBX5, TBX3	DBP	[11]
13	rs9549328	112981842	T	0.23	0.32	1.50E–08	313,787	MCF2L	SBP	[11]
14	rs12050260	23291885	T	0.35	0.19	2.60E–08	304,390	MYH6	PP	[11]
14	rs8904	35402011	A	0.38	0.31	1.31E–12	365,195	NFKBIA	SBP	[70]
14	rs9888615	52910822	T	0.29	−0.32	3.50E–10	326,235	FERMT2	SBP	[11]
14	rs8016306	63461828	A	0.8	0.34	3.70E–09	329,869	PPP2R5E	SBP	[11]
14	rs12434998	93989208	C	0.37	−0.19	1.64E–08	315,683	chr14mb94	PP	[11]
14	rs9323988	98121293	T	0.63	−0.21	4.10E–11	327,551	RP11–61O1.1	PP	[11]
15	rs1036477	48622729	G	0.1	−0.42	3.81E–08	149,967	FBN1	PP	[70]
15	rs7178615	66576734	A	0.37	−0.18	2.60E–10	318,076	RP11–321F6.1	DBP	[11]
15	rs1563894	68343437	NA	NA	0.09	3.00E–08	10,090	ITGA11	SBP	[72]
15	rs117539635	69390577	G	0.03	−0.65	2.15E–08	196,789	chr15mb69	DBP	[11]
15	rs1378942	74785026	C	0.35	0.42	2.69E–26	163,115	CYP1A1, ULK3	DBP	[9]
15	rs6495122	74833304	A	0.42	0.4	1.84E–10	NA	CSK, ULK3	DBP	[8]
15	rs187680191	76002970	T	0.0006	18.58	3.00E–09	19,546	NRG4	DBP	[71]
15	rs62012628	78777658	T	0.29	−0.24	5.10E–12	244,143	ADAMTS7	DBP	[11]
15	rs11634851	80736624	G	0.46	0.32	5.38E–14	374,208	FAM108C1	SBP	[70]
15	rs2521501	90894158	T	0.31	0.65	5.20E–19	127,208	FURIN, FES	SBP	[9]
15	rs12906962	94768842	T	0.68	−0.22	5.60E–14	319,952	chr15mb95	DBP	[11]
15	rs4984496	96092669	G	0.67	−0.18	2.86E–09	307,660	chr15mb96	DBP	[11]
16	rs12921187	4893018	T	0.43	−0.17	2.50E–10	326,469	PPL	DBP	[11]
16	rs13333226	20354332	A	0.81	0.85	1.50E–13	39,706	UMOD	HT	[25]
16	rs72799341	30925422	A	0.24	0.19	5.80E–09	324,502	FBXL19	DBP	[11]
16	rs56249585	65231799	T	0.53	0.18	8.98E–09	318,082	chr16mb65	PP	[11]
16	rs141767645	69869262	T	0.02	1.3	1.90E–08	174,313	NFAT5	PP	[11]
16	rs200337503	70084312	I	0.03	1.31	6.88E–13	193,318	NFAT5	PP	[11]
16	rs117006983	70721707	A	0.01	0.99	4.10E–12	250,766	VAC14	PP	[11]
16	rs11643209	75297146	T	0.42	−0.34	1.80E–12	309,242	CFDP1	SBP	[11]
16	rs8059962	81540592	T	0.42	−0.17	1.30E–09	319,839	CMIP	DBP	[11]
16	rs7500448	83012185	A	0.75	0.33	1.10E–19	321,958	CDH13	PP	[11]
17	rs12941318	1430304	T	0.49	−0.27	2.50E–08	299,739	CRK	SBP	[11]
17	rs7226020	6570508	T	0.56	−0.26	2.30E–14	303,389	KIAA0753	PP	[11]
17	rs5417	7281743	A	0.57	0.21	1.10E–13	319,299	TP53, SLC2A4	DBP	[11]
17	rs138643143	42557849	A	0.07	0.5	3.30E–09	229,161	KCNH4, HSD17B1	PP	[11]
17	rs62080325	43983263	A	0.66	−0.19	4.00E–08	315,689	PYY	PP	[11]
17	rs12946454	45130754	T	0.28	0.57	1.00E–08	77,690	PLCD3	SBP	[7]
17	rs551011992	45851264	G	0.24	−0.33	3.32E–08	275,778	GOSR2	SBP	[11]
17	rs17608766	46935905	C	0.14	0.55	1.97E–15	137,066	GOSR2	PP	[70]
17	rs79917357	48747312	A	0.17	0.34	5.33E–09	336,863	LOC105371811 –LOC105371812	SBP	[70]
17	rs585736	48796910	A	0.03	0.61	2.50E–11	301,845	HOXB7	PP	[11]
17	rs12940887	49325445	T	0.37	0.26	1.18E–08	144,603	ZNF652	DBP	[70]
17	rs16948048	49363104	G	0.39	0.31	8.24E+04	82,441	PHB, ZNF652	DBP	[7]
17	rs740698	62689790	T	0.56	−0.23	3.10E–12	311,450	MRC2	PP	[11]
17	rs4459609	63471587	A	0.61	−0.2	2.03E–14	361,581	CYB561, ACE	DBP	[70]
17	rs4308	63482264	A	0.37	0.21	6.80E–14	319,394	ACE	DBP	[11]
17	rs2467099	75952964	T	0.22	−0.31	3.30E–08	326,401	ACOX1	SBP	[11]
17	rs57927100	77321218	G	0.26	−0.31	4.04E–10	347,188	SPET9	SBP	[70]
18	rs7236548	45517785	A	0.18	0.35	2.00E–18	330,075	SLC14A2	PP	[11]
18	rs745821	50616484	T	0.76	0.19	1.40E–09	330,954	MAPK4	DBP	[11]
19	rs36047283	7255690	G	0.11	−0.8	3.25E–26	281,588	INSR	SBP	[70]
19	rs2116941	10223767	C	0.81	−0.22	2.77E–08	321,960	chr19mb10	PP	[11]
19	rs77279095	11415506	A	0.04	0.86	7.26E–09	224,215	RGL3	SBP	[11]
19	rs62104477	29804084	T	0.33	0.18	1.20E–09	320,347	CCNE1	DBP	[11]
19	rs9710247	40254542	G	0.45	0.16	1.61E–09	308,028	AKT2	DBP	[70]
20	rs6108168	8645624	A	0.25	−0.21	1.10E–11	327,368	PLCB1	DBP	[11]
20	rs1327235	10988382	G	0.46	0.3	1.41E–15	158,454	JAG1	DBP	[9]
20	rs6081613	19485263	A	0.28	0.26	1.60E–13	315,546	SLC24A3	PP	[11]
20	rs80346118	48794612	A	0.15	−0.27	1.10E–12	327,614	PREX1	DBP	[11]
20	rs6015450	59176062	G	0.12	0.9	3.87E–23	159,190	EDN3, GNAS	SBP	[9]
21	rs12627651	43340723	A	0.29	0.32	2.40E–09	121,169	CRYAA, SIK1	DBP	[70]
22	rs4819852	20000644	A	0.29	0.26	1.43E–13	367,460	ARVCF	PP	[70]
22	rs73161324	41642782	T	0.05	0.5	2.80E–11	267,722	XRCC6	PP	[11]
b Asians and Africans
Asians
1 rs880315		10736809	C	0.65	0.56	3.05E–10	32,611	CASZ1	DBP	[12]
1	rs10745332	112646431	A	0.82	0.96	2.52E–09	46,269	MOV10	SBP	[13]
2	rs1344653	19531084	A	0.53	−0.27	7.79E–12	220,853	OSR1	PP	[73]
2	rs1275988	26691496	T	0.53	−0.37	4.95E–21	236,311	KCNK3	OH	[73]
2	rs7604423	43155602	C	0.66	−0.21	2.40E–08	217,072	NR	DBP	[73]
2	rs6736587	81628601	C	0.16	−1.38	5.3E–08	NA	CTNNA2	OH	[74]
2	rs16849225	164050310	C	0.61	0.75	3.45E–11	49,511	GRB14, FIGN	SBP	[12]
3	rs820430	27507409	A	0.32	0.76	1.36E–12	79,318	SLC4A7	SBP	[13]
3	rs9810888	53601568	G	0.39	0.39	4.0E–12	77,555	CACNA1D	DBP	[13]
4	rs1902859	80236549	C	0.41	1.34	1.76E–22	45,856	FGF5	SBP	[13]
4	rs2014912	85794517	T	0.16	0.62	5.37E–17	242,456	ARHGAP24	SBP	[73]
4	rs6825911	110460482	C	0.51	0.39	8.96E–09	49,511	ENPEP	DBP	[12]
4	rs13143871	155698052	T	0.80	0.96	5.16E–08	45,737	GUCY1A3	SBP	[13]
5	rs1173766	32804422	C	0.60	0.63	1.95E–08	49,970	NPR3	SBP	[12]
5	rs13359291	123140763	A	0.31	0.53	8.88E–16	229,584	PRDM6	SBP	[73]
5	rs9687065	149011577	A	0.78	0.26	7.36E–11	259,216	ABLIM3, SH3TC2	DBP	[73]
6	rs2021783	32077074	C	0.79	0.49	2.18E–12	78,911	CYP21A2	DBP	[13]
6	rs1563788	43340625	T	0.31	0.51	2.22E–16	220,757	ZNF318	SBP	[73]
6	rs1474698	56199399	T	0.62	−0.20	4.52E–09	274,981	NR	PP	[73]
7	rs2107595	19009765	A	0.23	0.31	3.91E–11	209,305	HDAC9	PP	[73]
7	rs10260816	45970501	C	0.61	0.31	1.51E–14	207,070	IGFBP3	PP	[73]
7	rs17477177	106771412	T	0.77	−0.53	3.69E–12	99,344	PIK3CG	PP	[73]
10	rs4919669	102712218	A	0.43	−0.65	2.63E–08	NA	ARL3	SBP	[74]
10	rs284844	102794772	A	0.49	−0.75	1.05E–11	NA	WBP1L	SBP	[74]
10	rs4409766	102856906	T	0.71	1.24	6.08E–17	46,030	CYP17A1	SBP	[13]
10	rs11191548	103086421	T	0.74	1.18	3.94E–17	41,315	CNNM2	SBP	[12]
10	rs11191580	103146454	T	0.74	0.97	4.44E–15	NA	NT5C2	SBP	[74]
11	rs4757391	16281393	C	0.28	0.88	5.20E–9	46,336	SOX6	SBP	[13]
11	rs751984	61510774	T	0.79	0.33	7.66E–12	233,082	LRRC10B, SYT7	MAP	[73]
12	rs12579720	20020830	C	0.32	−0.32	2.2E–16	218,606	PDE3A	DBP	[73]
12	rs17249754	89666809	G	0.64	1.17	7.72E–20	40,719	ATP2B1	SBP	[12]
12	rs3184504	111446804	T	0.46	0.54	2.20E–10	35,342	SH2B3	DBP	[73]
12	rs653178	111569952	T	0.50	−0.55	1.20E–08	35,342	ATXN2	DBP	[73]
12	rs11066280	112379979	T	0.75	1.01	1.32E–35	46,957	HECTD4	DBP	[12]
12	rs35444	115114632	A	0.75	0.52	9.62E–08	29,746	TBX3	DBP	[12]
12	rs11067763	115760536	A	0.62	0.51	2E–18	79,651	MED13L	DBP	[13]
17	rs2240736	61408032	T	0.66	0.35	2.20E–16	217,197	C17orf82, TBX2	MAP	[73]
18	rs403814	6282594	A	NA	1.15	6.13E–09	NA	L3MBTL4	HT	[75]
19	rs740406	2232222	A	0.87	−0.55	3.10E–15	193,219	PLEKHJ1, DOT1L	PP	[73]
20	rs1887320	10985350	A	0.53	0.78	1.48E–08	46,123	JAG1	SBP	[13]
Africans 3	rs1717027	41946428	T	0.64	0.49	4.90E–13	29,322	ULK4	HT	[76]
6	rs13209747	126794309	T	0.19	0.56	2.40E–11	28,708	RSPO3	DBP	[76]
6	rs76987554	133759717	C	0.09	−1.69	2.28E–10	62,297	TARID, TCF21	SBP	[15]
6	rs17080102	150683634	C	0.1	−0.74	1.90E–11	29,323	PLEKHG1	DBP	[76]
7	rs6969780	27119517	C	0.3	0.46	3.27E–10	85,397	HOXA	DBP	[15]
7	rs17428471	27298248	T	0.14	1.20	2.00E–12	29,326	HOXA, EVX1	SBP	[76]
7	rs11563582	27312031	A	0.13	0.67	1.71E–11	84,816	EVX1, HOXA	DBP	[15]
7	rs7801190	100860471	C	0.72	1.31	3.40E–08	10,771	SLC12A9	HT	[77]
8	rs7006531	94098516	G	0.85	−1.02	5.96E–12	72,887	CDH17	PP	[15]
8	rs78192203	141364973	T	0.2	0.84	4.00E–11	62,681	GPR20	DBP	[15]
9	rs115795127	83378986	T	0.89	0.17	1.13E–08	32,149	FRMD3	HT	[15]

Chr, chromosome; EA, effect allele; EAF, effect allele frequency; SBP, systolic blood pressure; DBP, diastolic blood pressure; PP, pulse pressure; MAP, mean arterial pressure; HT, hypertension; OH, orthostatic hypotension; NA, not available.