Table I.

Association of NEDD8 expression and clinicopathologic characteristics of the HCC patients.

Variables	No. of cases	High NAE1 level	Low NAE1 level	P-value
Age (years)				0.313
<55	110	45	65
≥55	227	80	147
Sex				0.575
Female	107	42	65
Male	230	83	147
Recurrence				0.183
Present	154	63	91
Absent	183	62	121
Histologic grade				0.011a
G1-G2	210	67	143
G3-G4	127	58	69
Tumor stage				0.763
T1-T2	253	95	158
T3-T4	84	30	54
Clinical stage				0.743
I–II	250	94	156
III–IV	87	31	56

^aP<0.05. HCC, hepatocellular carcinoma.