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. 2016 Feb 9;2016(2):CD012079. doi: 10.1002/14651858.CD012079
Methods Parallel‐group RCT
Participants Inclusion: grade 2 or 3 cystocele
Exclusion: urinary incontinence, previous gynaecological operation, concomitant rectocele or enterocele, recurrent cystocele
Interventions Polypropylene mesh surgery (20 women) vs AC (20 women)
Outcomes Assessed at 6 weeks, 6 months, 1 year
Reports the following review outcomes at 1 year:
  • Awareness of prolapse (bulging) 5/20 vs 1/20

  • Repeat prolapse (> stage 1 on examination) 1/20 vs 5/20

  • Mesh erosion n = 3

  • Surgery for mesh erosion n = 3

  • Operating time 44 ∓ 5 21 ∓ 2

  • De novo urinary incontinence 0/20 vs 2/20

  • Days in hospital: reports means but no SDs

Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk "Allocated by computer programme"
Allocation concealment (selection bias) Unclear risk Method not described
Blinding of participants and personnel (performance bias) All outcomes Unclear risk Blinding not mentioned
Blinding of outcome assessment (detection bias) All outcomes Unclear risk Blinding not mentioned
Incomplete outcome data (attrition bias) All outcomes Unclear risk All 40/40 randomised women were included in analysis
Selective reporting (reporting bias) Low risk Reports main review outcomes
Other bias Low risk Reports "no conflict of interest". No other potential bias identified