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. 2019 Apr 29;21:107. doi: 10.1186/s13075-019-1878-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Type I IFN activity and levels of IFN-α, IFN-γ and IFN-λ1 in SLE patients and population controls. Type I IFN activity in vitro (a) and IFN-γ levels (b), IFN-α (c) and IFN-λ1 (d) were all higher in SLE patients then population controls (Mann-Whitney U test). The dashed boxes indicate individuals with high levels (> 75th percentile of patient measures) of each investigated IFN