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. 2019 Apr 29;12:39. doi: 10.1186/s13041-019-0460-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Gene-gene interaction networks. a Gene-gene interaction networks were generated based on the dysregulated genes in the hippocampus by using Gene Signal Network software. b Gene-gene interaction networkswere generated based on the dysregulated genes in the cortex. Red and green colored genes represent up- and down-regulated genes, respectively. Letter a represents activation, b represents binding/associated, c represents compound, inh represents inhibition, ind represents indirect effect, u represents ubiquitination, m represents missing interaction, ex represents expression, p represents phosphorylation, rep represents repression, and disso represents dissociation