Fig. 1: preferred reporting items for systematic reviews and meta-analyses (PRISMA) diagram, showing the different phases of the bibliographic survey and consolidation of the data regarding the insecticide resistance of Brazilian Aedes aegypti populations between 1985 and 2017. The following criteria were adopted for the inclusion of articles in the systematic review: (1) articles with a title and abstract related to the theme of this study were included. (2) Consistency of susceptibility status data against temephos or deltamethrin: for qualitative trials, those studies reporting the diagnostic concentration(s) of pesticide tested and the percent mortality obtained were included; for quantitative trials, those reporting LCs (50, 90, and 95) and the corresponding RRs were included. (3) Field collection: articles were included that provided information on the field sample size collected, taking into account their representativeness in relation to the municipality area and the collection period. For samples collected in districts or in other municipality subdivisions, the average RR of the reported values was considered; in these cases, the entire range of LC confidence intervals was used. Papers that did not mention the year of sample collection were discarded, except for those described by Braga et al.⁽⁵⁴⁾, whose records are in our team’s possession. (4) The articles already covered by Moyes et al.⁽²⁹⁾ were excluded from the present analysis.