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. Author manuscript; available in PMC: 2019 Apr 30.
Published in final edited form as: J Urol. 2011 Mar 21;185(5):1894–1898. doi: 10.1016/j.juro.2010.12.095

Figure 2.

Figure 2

MAPK pathway is active during urethral development, and its upstream tyrosine kinases Ntrk1 and Ntrk2 are expressed in urethral epithelium. All mice were fed normal chow not supplemented with genistein. Western blot analysis of whole cell lysates derived from isolated E 17.5 male fetal urethras are shown using antibodies recognizing Ntrk1 or Ntrk2 (a), or phospho-ERK1,2 or total ERK1,2 (b). Serial tissue sections of urogenital sinus (UGS) and urethras (c, top panels) and through genital tubercle (c, middle and bottom panels) of E 17.5 male fetuses stained either with no primary antibody or with antibodies recognizing Ntrk1 or Ntrk2.