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. Author manuscript; available in PMC: 2020 Jan 10.
Published in final edited form as: Int J Pharm. 2018 Nov 5;554:212–223. doi: 10.1016/j.ijpharm.2018.11.011

Figure 8.

Figure 8.

Ex vivo UPE NPs transfer efficiency under flow conditions. (A) In-vitro closed loop recirculation model to quantify the retention of nanoparticles on the arterial wall after transferring from coated balloons onto the arterial wall under flow conditions. Main components are (a) rat artery (2 cm in length), (b) silicon tubing, and (c) peristaltic pump. (B) Fluorescence imaging of NPs transferred to arteries and (C) spectrophotometric analysis of the studied artery homogenate after NP transfer observed that hydrogel coated balloons transferred a significantly higher amount of nanoparticles to the arterial wall compared to those of dip and LbL coatings. *p<0.05 vs. LbL, §p<0.05 vs. Hydrogel, n=3 replicates were used for these studies.