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. 2019 Apr 23;10:386. doi: 10.3389/fphar.2019.00386

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Copyright © 2019 Luo, Bian, Zhang, Xia, Liu, Chen, Ke, Wu and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Shengui Sansheng San extraction regulated the expressions of p-PDHA1, ACS and CS and enhanced pyruvate, acetyl-CoA, citrate and ATP yields in infarcted region (n = 3). (A–D) Representative belts of western blot and quantitative analysis of p-PDHA1, ACS and CS were presented at day 7. (E–H) Results of pyruvate, acetyl-CoA, citrate and ATP by ELISA in infarcted region. Data presented as mean ± standard deviation. ^∗∗p < 0.01, ^∗∗∗p < 0.001 vs. sham group; ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 vs. MCAo group; ^&p < 0.05, ^&&p < 0.01 vs. low group; ^xxp < 0.01, ^xxxp < 0.001 vs. middle group.