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. 2019 Apr 10;11:2963–2976. doi: 10.2147/CMAR.S202664

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© 2019 Han et al.

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miR-34a suppressed the proliferation and colony formation of Hep3B and SNU-449. Relative inhibition rates of Hep3B (A) and SNU-449 (B) in response to miR-34a, and mock group were calculated by comparing the OD value of miR-34a mimic or mock to NC, at 48, 72, 96, and 120 hrs, respectively. The representative colony formation of SNU-449 (C) and Hep3B (D) cells transfected by miR-34a and control mimics. The relative colony formation efficiency also showed significant reduction of amount of colonies of SNU-449 and Hep3B (E) in miR-34a mimic groups. Data are presented as the mean±SD (miR-34a mimic vs control mimic).

Abbreviation: NS, non-significant.