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The overview of TET attenuated BUP-induced neurotoxicity in SH-SY5Y cells. BUP-induced SH-SY5Y cell apoptosis and oxidative damage were reversed by TET treatment. In addition, TET induced SH-SY5Y cell autophagy, and autophagy exerts prosurvival and antioxidant roles.
Abbreviations: BUP, bupivacaine; monodansylcadaverine; TET, tetramethylpyrazine.
