Table 3.
Comparison of incidence and HR for mortality stratified by age, sex, and comorbidity between poststroke and comparison cohorts
| Comparison cohort N=27,207 |
Poststroke | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total stroke (N=13,603) | Poststroke non-epilepsy (N=11,952) | Poststroke epilepsy (N=1,651) | |||||||||
| Event (N) | Rate | Event (N) | Rate | Adjusted HR (95% CI)* | Event (N) | Rate | Adjusted HR (95% CI)* | Event (N) | Rate | Adjusted HR (95% CI)* | |
| Age, years | |||||||||||
| 40–64 | 717 | 12.2 | 817 | 31.2 | 2.72 (2.46, 3.01) | 604 | 26.2 | 2.32 (2.08, 2.58) | 213 | 66.4 | 5.38 (4.61, 6.28) |
| 65–74 | 1,526 | 31.1 | 1,539 | 74.6 | 2.50 (2.33, 2.69) | 1,257 | 66.7 | 2.24 (2.08, 2.41) | 282 | 157.4 | 5.28 (4.65, 6.00) |
| ≥75 | 3,877 | 80.3 | 2,808 | 150.4 | 1.94 (1.85, 2.04) | 2,338 | 138.0 | 1.79 (1.70, 1.88) | 470 | 272.6 | 3.38 (3.07, 3.72) |
| P for interaction | <0.001 | <0.001 | |||||||||
| Sex | |||||||||||
| Female | 2,515 | 35.8 | 2,143 | 72.2 | 2.12 (2.00, 2.24) | 1,751 | 65.3 | 1.91 (1.80, 2.04) | 392 | 137.8 | 3.99 (3.59, 4.45) |
| Male | 3,605 | 42.0 | 3,021 | 84.3 | 2.12 (2.02, 2.23) | 2,448 | 76.6 | 1.90 (1.80, 2.00) | 573 | 147.8 | 4.28 (3.91, 4.67) |
| P for interaction | 0.90 | 0.40 | |||||||||
| Comorbidity | |||||||||||
| None | 70 | 29.2 | 49 | 47.7 | 1.88 (1.31, 2.72) | 43 | 43.0 | 1.69 (1.16, 2.47) | 6 | 226.4 | 16.1 (6.79, 38.4) |
| With any one | 6,050 | 39.4 | 5,115 | 79.3 | 2.08 (2.00, 2.16) | 4,156 | 71.9 | 1.86 (1.79, 1.94) | 959 | 143.2 | 4.20 (3.92, 4.49) |
| P for interaction | 0.26 | 0.84 | |||||||||
Notes: Rate, per 1,000 person-years; *variables found to be statistically significant in the univariable model were further included in the multivariable model.