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. 2019 Apr 11;12:2635–2648. doi: 10.2147/OTT.S193771

Table 2.

Clinicopathological characteristics for the entire cohort and subgroups according to AST/ALT ratio (AST/ALT ratio <1.23 are low group, otherwise high group) after propensity score matching

Characteristics Entire cohort Low AST/ALT High AST/ALT P-value
Number of subjects 602 301 301
Preoperative characteristics
Age, years 66.77±9.90 65.98±9.79 67.56±9.96 0.051
Aged >65 years 385 (64.0%) 181 (60.1%) 204 (67.8%) 0.051
Gender (male) 285 (47.3%) 147 (48.8%) 138 (45.8%) 0.463
Body mass index 24.58±3.52 24.67±3.34 24.49±3.69 0.516
Diabetes 99 (16.4%) 51 (16.9%) 48 (15.9%) 0.742
Hypertension 224 (37.2%) 114 (37.9%) 110 (36.5) 0.736
Coronary disease 67 (11.1%) 29 (9.6%) 38 (12.6%) 0.243
Alcohol 6 5(10.8%) 33 (11.0%) 32 (10.6%) 0.896
Tobacco 94 (15.6%) 47 (15.6%) 47 (15.6%) 1.000
Hydronephrosis 296 (49.2%) 142 (47.2%) 154 (51.2%) 0.328
Tumor location (pelvis) 310 (51.5%) 151 (50.0%) 159 (52.8%) 0.514
Tumor size (>5cm) 88 (14.6%) 40 (13.3%) 48 (15.9%) 0.356
Postoperative characteristics
Pathological T Stage 0.492
Ta 6 (1.0%) 1 (0.3%) 5 (1.7%)
T1 234 (38.9%) 115 (38.2%) 119 (39.5%)
T2 196 (32.6%) 97 (32.2%) 99 (32.9%)
T3 148 (24.6%) 78 (25.9%) 70 (23.3%)
T4 18 (3.0%) 10 (3.3%) 8 (2.7%)
Pathological N Stage 0.120
N0 561 (93.2%) 280 (93.0%) 281 (93.4%)
N1 37 (6.1%) 17 (5.6%) 20 (6.6%)
N2 4 (0.7%) 4 (1.3%) 0 (0.0%)
Cellular grade 0.653
G1 15 (2.5%) 8 (2.7%) 7 (2.3%)
G2 342 (56.8%) 176 (58.5%) 166 (55.1%)
G3 245 (40.7%) 117 (38.9%) 128 (42.5%)
Lymphatic microvascular invasion 25 (4.15%) 11 (44.0%) 14 (56.0%) 0.540
Tumor major diameter 3.39±2.26 3.33±2.38 3.56±2.33 0.542
Tumor necrosis 75 (12.5%) 39 (13.0%) 36 (12.0%) 0.711
Tumor hemorrhage 19 (3.2%) 8 (2.7%) 11 (3.7%) 0.484
Tumor architecture (sessile) 109 (18.1%) 55 (18.3%) 54 (17.9%) 0.916
Squamous metaplasia 51 (8.5%) 28 (9.3%) 23 (7.6%) 0.464
Sarcomatoid differentiation 26 (4.3%) 13 (4.3%) 13 (4.3%) 1.000
Glandular differentiation 28 (4.7%) 14 (4.7%) 14 (4.7%) 1.000