Table 1.

Evaluation of combination of PTX with emodin in NSCLC (72 hr treatment)

Combination strategy	IC50 value of PTX	95% CI values	DRI
PTX (range 0 from 32 µM)	IC50 = 10.08 ± 1.04 µM	–	–
PTX +5 µM emodin	IC50 = 8.65 ± 1.01 µM	0.980	1.165
PTX +10 µM emodin	IC50 = 4.68 ± 0.71 µM	0.709	2.154
PTX +20 µM emodin	IC50 = 2.33 ±0.52 µM	0.720	4.326
PTX +40 µM emodin	IC50 = 1.33 ± 0.33 µM	1.109	7.579

Abbreviations: DRI, dose reduction index; NSCLC, non-small-cell; PTX, paclitaxel.