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. 2019 Apr 12;11:3171–3185. doi: 10.2147/CMAR.S195424

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© 2019 Gao et al.

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Silencing of SLC5A1 reduced in vivo pancreatic cancer growth. (A) Representative images of Panc-2-implanted mice captured every week throughout 3 weeks of experiment. Knockdown of SLC5A1 decreased in vivo tumor growth. (B) Kaplan-Meier survival plots of mice implanted with Panc-2 with or without SLC5A1 knockdown. Knockdown of SLC5A1 enhanced mice survival. (C) Weekly monitoring of body weight of mice. There were no significant changes in body weight throughout the study period. (D) The weight of tumour-bearing pancreas was reduced in mice implanted with SLC5A1 knockout Panc-2. **P<0.01.