Table 3.
The detailed information of the top 20 upregulated DEGs
| Upregulated Gene | Gene ID | Location | Q value | Log2 fold-change (CPIP/Sham) | Official gene name (NCBI) |
|---|---|---|---|---|---|
| Sprr1a | 499,660 | 2:192,669,143–192,671,059 | 1.17E-45 | 8.89909 | Small proline-rich protein 1A |
| Crisp1 | 64,827 | 9:24,356,577–24,383,679 | 1.27E-43 | 8.817702 | Cysteine-rich secretory protein 1 |
| Lce1f | 499,663 | 2:192,990,607–192,992,193 | 2.56E-37 | 8.54087 | Late cornified envelope 1F |
| Hamp | 84,604 | 1:89,368,021–89,369,960 | 5.19E-59 | 8.155005 | Hepcidin antimicrobial peptide |
| Vip | 117,064 | 1:42,169,307–42,177,582 | 2.17E-163 | 8.034563 | Vasoactive intestinal peptide |
| Il6 | 24,498 | 4:3,043,231–3,047,807 | 8.81E-19 | 7.350197 | Interleukin 6 |
| Serpinb2 | 60,325 | 13:27,449,907–27,463,015 | 4.85E-72 | 6.701509 | Serpin family B member 2 |
| Npy | 24,604 | 4:79,557,856–79,565,059 | 0 | 6.391931 | Neuropeptide Y |
| Tgm1 | 60,335 | 15:34,378,136–34,393,150 | 0 | 6.325616 | Transglutaminase 1 |
| Hpd | 29,531 | 12:38,828,606–38,839,956 | 1.17E-18 | 6.258274 | 4-hydroxyphenylpyruvate dioxygenase |
| Slc30a3 | 366,568 | 6:26,629,752–26,650,106 | 1.54E-17 | 6.160094 | Solute carrier family 30 member 3 |
| Il24 | 170,819 | 13:47,618,451–47,623,849 | 7.18E-14 | 5.791706 | Interleukin 24 |
| RT1-N1 | 24,748 | Unknown | 2.33E-07 | 5.765234 | RT1 class Ib, locus N1 |
| Serpina3n | 24,795 | 6:128,073,344–28,080,878 | 0 | 5.390968 | Serine (or cysteine) peptidase inhibitor, clade A, member 3N |
| Stac2 | 363,674 | 10:85,988,367–86,004,209 | 0 | 5.345099 | SH3 and cysteine rich domain 2 |
| Ucn | 29,151 | 6:26,602,144–26,602,974 | 2.94E-54 | 5.264588 | Urocortin |
| Cldn4 | 304,407 | 12:24,761,210–24,763,008 | 1.49E-105 | 5.205793 | Claudin-4 |
| Nps | 100,360,071 | 1:207,508,414–207,512,195 | 2.98E-04 | 4.817702 | Neuropeptide S |
| Kbtbd6 | 306,073 | 15–61,731,574-61,733,331 | 3.13E-04 | 4.808397 | Kelch repeat and BTB domain-containing protein 6 |
| Vtcn1 | 295,322 | 2:203,200,435–203,274,264 | 1.16E-24 | 4.724592 | V-set domain-containing T-cell activation inhibitor 1 |