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. 2019 Apr 18;12:2999–3009. doi: 10.2147/OTT.S202523

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© 2019 Wang et al.

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FOXM1 silencing enhances miR-216b-induced effects in NSCLC cells. (A) FOXM1 protein expression was analyzed by Western blot. (B) The proliferation of A549, H460, and H1299 cells co-transfected with FOXM1 siRNAs and/or miR-216b mimics was measured through CCK-8 assay. (C and D) The migration and invasion of A549, H460, and H1299 cells co-transfected with FOXM1 siRNAs and/or miR-216b mimics were analyzed by wound healing and Transwell invasion assay, respectively. Data were represented as mean±SD. * P < 0.01 vs miR-216b mimics+si-control; ^# P < 0.01 vs miR-NC+si-control.