The effects of C36D on CORT‐induced cGMP reduction in concentration‐ and time‐dependent manners in the HT‐22 cells. A, HT‐22 cells were treated with 100 μmol/L CORT for 30 min and added C36D for 24 h. B, HT‐22 cells were treated with 100 μmol/L CORT for 30 min and then with C36D for the indicated periods. The results represent the mean ± SEM, n = 6. *P < 0.05 and **P < 0.01, compared to control group. #
P < 0.05 and ##
P < 0.01, compared to vehicle‐treated CORT group. $
P < 0.05, compared to C36D (10−7 mol/L)‐treated CORT group