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. 2017 Dec 6;24(2):115–125. doi: 10.1111/cns.12781

Figure 4.

Figure 4

Liquid chromatography‐mass spectrometry analysis shows the effect of finasteride on the contents of dopamine and its metabolites in adolescent rats. **P < 0.01, *P < 0.05. It is shown that finasteride treatment at doses of 25 and 50 mg/kg significantly reduces the contents of dopamine (A‐D) in frontal cortex, hippocampus, CPu and Acb and its metabolites including DOPAC (E‐F) and HVA (G‐H) in CPu and Acb compared to control group. Abbreviations: DA, dopamine; DOPAC, dihydroxy phenyl acetic acid; HVA, homovanillic acid; Hip. Hippocampus; CPu, caudate putamen; Acb, nucleus accumbens. (n = 7 for each group)