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Hypothermia induces changes in mRNA expression of M1 and M2 phenotypic markers after MCAO. Total RNA was extracted from ischemic ipsilateral and sham brains at day 14 after MCAO and processed for RT‐PCR. A, Expression levels of mRNA for M1 markers. B, Expression levels of mRNA for M2 markers. Data are expressed as fold change versus 37°C + sham group; n = 5 per group. *P < 0.05, **P < 0.01, ***P < 0.001 versus sham groups; #P < 0.05 and ##P < 0.01 versus 37°C + MCAO
