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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Neuromuscul Disord. 2018 Jun 27;28(9):778–786. doi: 10.1016/j.nmd.2018.06.007

Fig. 2. Comparison of patients of varying ages.

Fig. 2

Affected are represented as diamonds, carriers as squares, and unaffected as triangles. (a) IBMFRS Score v. Age. IBMFRS declines in affected individuals with older individuals in this cohort, while unaffected stays constant. The trendline for unaffected individuals is solid (y = 0.0009x + 39.838, p-value = 0.92). The trendline for carriers is dotted (y = −0.1735x + 45.264, p-value = 0.31). The trendline for affected individuals is dashed (y = −0.5363x + 55.096, p-value = 0.01). (b) 6MWT v. Age. Decline in all groups at older age, regardless of condition. The trendline for unaffected individuals is solid (y = −4.0252x + 744.03, p-value = 0.02). The trendline for carriers is dotted (y = −7.828x + 796.11, p-value = 0.12). The trendline for affected individuals is dashed (y = −7.4643x + 758.23, p-value = 0.08). (c) Manual Muscle Test Total MRC Score v. Age. MRC score declines for older affected individuals, while unaffected stays constant. The trendline for unaffected individuals is solid (y = −0.0591x + 282.6, p-value = 0.40). The trendline for carriers is dotted (y = 0.0155x + 266.35, p-value = 0.99). The trendline for affected individuals is dashed (y = −3.4974x + 385.03, p-value = 0.01).