Table 2. Volumetric Results in the Derivation and Validation Cohorts.
| Cohort | SF Group | NSF Group | P Valuea |
|---|---|---|---|
| Derivation | |||
| No. of patients | 46 | 61 | NA |
| Preoperative ipsilateral volume, median (IQR), ml | |||
| Piriform cortex | 0.5 (0.4-0.6) | 0.4 (0.3-0.5) | .02 |
| Hippocampus | 1.9 (1.7-2.3) | 1.9 (1.6-2.3) | .39 |
| Amygdala | 1.0 (0.9-1.1) | 1.0 (0.8-1.1) | .57 |
| Entorhinal cortex | 2.2 (1.9-2.5) | 2.2 (2.0-2.4) | .75 |
| Resected proportion, median (IQR), % | |||
| Piriform cortex | 83 (64-91) | 52 (32-70) | <.001 |
| Hippocampus | 57 (47-64) | 58 (36-66) | .39 |
| Amygdala | 49 (37-62) | 48 (36-60) | .60 |
| Entorhinal cortex | 82 (72-89) | 82 (71-87) | .51 |
| Resection volume, median (IQR), mL | 49 (42-58) | 50 (42-58) | .92 |
| Validation | |||
| No. of patients | 12 | 19 | NA |
| Piriform cortex resected proportion, median (IQR), % | 67 (55-77) | 26 (6-45) | <.001 |
| Thomas Jefferson University | |||
| No. of patients | 6 | 12 | NA |
| Piriform cortex resected proportion, median (IQR), % | 60 (41-75) | 28 (15-54) | .04 |
| University of Pennsylvania | |||
| No. of patients | 6 | 7 | NA |
| Piriform cortex resected proportion, median (IQR), % | 70 (62-81) | 11 (6-45) | .008 |
Abbreviations: IQR, interquartile range; NA, not applicable; NSF, non–seizure-free; SF, seizure-free.
a
Analyzed with Mann-Whitney test, reporting 2-sided P values.