Table 2.

Nonalcoholic Fatty Liver Disease

Diagnosis

Elevated serum liver enzymes (AST, ALT, GGT) or

Imaging study with evidence of fatty content and minimal to no alcohol intake and

Negative results for viral hepatitis, autoimmune disease, congenital liver disease, and any other plausible explanation

Liver biopsy with evidence of fatty content with or without inflammation or fibrosis and minimal to no alcohol intake

Management

Lifestyle modification (weight loss, physical exercise, diet with calories restriction)

Insulin‐sensitizing agents (e.g., biguanides and thiazolidinedione)

Others (e.g., antioxidants, lipid‐lowering agents, and ursodeoxycholic acid)

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma‐glutamyltransferase.