Table 1.
Characteristic | Total, N = 1285 | Q1: 2008–2010, n = 260 | Q2: 2011, n = 251 | Q3: 2012, n = 266 | Q4: 2013, n = 261 | Q5: 2014, n = 248 | P Value |
---|---|---|---|---|---|---|---|
Age, y | 82 ± 7 | 83 ± 7 | 83 ± 8 | 82 ± 7 | 82 ± 7 | 82 ± 8 | 0.165 |
Male sex | 43 | 40 | 39 | 40 | 50 | 46 | 0.031 |
STS score | 5.5 ± 3.6 | 6.7 ± 4.9 | 5.4 ± 3.4 | 5.1 ± 3.5 | 5.4 ± 3.9 | 4.8 ± 2.8 | <0.001 |
DM | 36 | 36 | 29 | 34 | 37 | 42 | 0.039 |
HTN | 88 | 83 | 89 | 91 | 89 | 87 | 0.096 |
Dyslipidemia | 81 | 80 | 79 | 78 | 85 | 82 | 0.380 |
PVD | 12 | 14 | 16 | 10 | 9 | 10 | 0.079 |
COPD | 19 | 25 | 20 | 18 | 19 | 14 | 0.049 |
Current smoker | 6 | 5 | 9 | 5 | 7 | 3 | 0.122 |
“Porcelain” aorta | 5 | 5 | 6 | 5 | 3 | 6 | 0.821 |
AF | 31 | 30 | 25 | 32 | 30 | 38 | 0.044 |
CAD | 51 | 52 | 51 | 48 | 56 | 48 | 0.283 |
MI | 18 | 17 | 16 | 19 | 24 | 13 | 0.025 |
PCI | 33 | 31 | 34 | 30 | 41 | 31 | 0.090 |
CABG | 20 | 26 | 16 | 18 | 21 | 18 | 0.026 |
PPM | 10 | 7 | 6 | 8 | 14 | 11 | 0.019 |
ICD | 1 | 2 | 1 | 2 | 2 | 1 | 0.837 |
CKD | 25 | 27 | 23 | 25 | 27 | 23 | 0.672 |
Hgb, g/dL | 12 ± 1 | 12 ± 2 | 12 ± 1 | 12 ± 2 | 12 ± 2 | 12 ± 2 | 0.801 |
Frailty | 17 | 28 | 10 | 11 | 15 | 24 | <0.001 |
NYHA class | |||||||
II | 16 | 14 | 17 | 13 | 22 | 18 | 0.002 |
III | 56 | 62 | 57 | 63 | 46 | 54 | |
IV | 24 | 20 | 24 | 22 | 31 | 26 | |
Mean aortic valve area, cm2 | 0.7 ± 0.16 | 0.64 ± 0.16 | 0.69 ± 0.19 | 0.70 ± 0.20 | 0.71 ± 0.19 | 0.74 ± 0.19 | <0.001 |
Mean aortic valve gradient, mm Hg | 47 ± 16 | 47 ± 16 | 48 ± 15 | 48 ± 17 | 48 ± 16 | 46 ± 18 | 0.311 |
Peak aortic valve gradient, mm Hg | 76 ± 23 | 77 ± 24 | 78 ± 24 | 76 ± 23 | 77 ± 24 | 72 ± 22 | 0.073 |
LVEF <50% | 39 | 48 | 36 | 37 | 32 | 39 | 0.065 |
Abbreviations: AF, atrial fibrillation; CABG, coronary artery bypass grafting surgery; CAD, coronary artery disease; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; Hgb, hemoglobin; HTN, hypertension; ICD, implantable cardioverter‐defibrillator; LVEF, left ventricular ejection fraction; MI, myocardial infarction; NYHA, New York Heart Association; PCI, percutaneous coronary intervention; PPM, permanent pacemaker; PVD, peripheral vascular disease; Q, quintile; SD, standard deviation; STS, Society of Thoracic Surgeons; TAVI, transcatheter aortic valve implantation.
Categorical variables are presented as % and continuous variables are presented as mean ± SD.