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. 2019 Apr-Jun;11(2):187–191.

Table 2.

Allele and genotype distribution of TYK2 gene rs34536443 SNP in RA patients and healthy controls

SNP Allele/Genotype RA(n=700) n (%) Control (n=700) n (%) OR (95% CI) p-value
rs34536443
C 31 (1.70%) 23 (2.61%) 1.35 (0.78–2.33) 0.27
G 1369 (98.30%) 1377 (97.39%) Reference
CC 1 (0.14%) 0 (0%) 3 (0.12–73.98) 0.50
CG 8 (1.14%) 7 (1%) 0.14 (0.41–3.17) 0.79
CC+CG 9 (1.28%) 7 (1%) 1.28 (0.47–3.48) 0.61
GG 691 (98.71%) 693 (99%) Reference
HWE p= 0.05

RA: Rheumatoid Arthritis; HWE: Hardy–Weinberg Equilibrium