Table 4.

Association of TYK2 gene polymorphism with RA susceptibility in different populations

Ethnicity	Number of cases	Allele	Odds ratio	p-value	Reference
European	11,475	G	0.62	2.3×10− 14	(8)
European (US, UK, Germany)	2816	G	0.56 (0.47–0.67)	1×10− 10	(17) (JIA)
Greek	125	C	2.45 (0.53–11.55)	0.34	(18) (JIA)
Greek	392	C	0.60 (0.27–1.35)	0.25	(19)
Iranian	700	C	1.35 (0.78–2.33)	0.27	Present study

JIA: Juvenile Inflammatory Arthritis