Table 4.
Association of TYK2 gene polymorphism with RA susceptibility in different populations
Ethnicity | Number of cases | Allele | Odds ratio | p-value | Reference |
---|---|---|---|---|---|
European | 11,475 | G | 0.62 | 2.3×10− 14 | (8) |
European (US, UK, Germany) | 2816 | G | 0.56 (0.47–0.67) | 1×10− 10 | (17) (JIA) |
Greek | 125 | C | 2.45 (0.53–11.55) | 0.34 | (18) (JIA) |
Greek | 392 | C | 0.60 (0.27–1.35) | 0.25 | (19) |
Iranian | 700 | C | 1.35 (0.78–2.33) | 0.27 | Present study |
JIA: Juvenile Inflammatory Arthritis