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. 2019 Apr-Jun;11(2):130–148.

Table 1.

Motif discovery algorithms

No. Algorithm Operating principle Ref.
Enumerative approach
1 YMF (29)
2 DREME Simple word- based (9)
3 oligonucleotide analysis (30)
4 CisFinder (10)
5 By Thomas et al Simple word-based with Clustering technique (31)
6 POSMO (32)
7 Weeder (7)
8 FMotif (11)
9 By G. Pavesi (33)
10 MITRA Tree-based (34)
11 CENSUS (35)
12 RISOTTO (36)
13 SLI-REST (37)
14 DRIMust (38)
15 MCES Tree based with clustering technique (12)
16 WINNOWER (39)
17 Pruner (40)
18 cWINNOWER (41)
19 By Sze et al (42)
20 RecMotif Graph-theoretic (43)
21 ListMotif (44)
22 TreeMotif (45)
23 GWM (46)
24 GWM2 (47)
25 Voting (48)
26 PMS1 (49)
27 PMS2 (49)
28 PMS3 (49)
29 By Sze et al (50)
30 PMSi (51)
31 PMSP Fixed candidates (51)
32 Stemming (52)
33 PMS4 (53)
34 PMS5 (54)
35 PMS6 (55)
36 PairMotif (56)
37 iTriplet (57)
38 PMSPrune (58)
39 Pampa (59)
40 PMS3p (60)
41 Provable Modified candidate (61)
42 qPMSPruneI (62)
43 qPMS7 (62)
44 By Tanaka et al (63)
45 Random projection (64)
46 Uniform projection Hashing (65)
47 Low-dispersion projection (66)
48 MULTIPROFILER Extended sample-driven (ESD) (67)
49 Pattern Branching (68)
50 Ref Select Reference selection (69)
Probabilistic approach
51 MEME (14)
52 STEME EM (15)
53 EXTREME (16)
54 Profile Branching (68)
55 APMotif EM with clustering (70)
56 AlignACE (17)
57 SPWDM (71)
58 By Lawrence et al Gibbs sampling (72)
59 Motif- Sampler (73)
60 BioProspector Gibbs Sampling with hidden markov (18)
62 MITSU (74)
63 MCEMDA Stochastic Expectation Maximization (sEM) (75)
64 SEAM (76)
65 By Jensen et al (13)
66 LOGOS (77)
67 BaMM (78)
68 By Jääskinen et al (79)
69 By Frith et al Baysian approach (80)
70 SBaSeTraM (81)
71 By Wakefield et al (82)
72 MotifCut (83)
73 MCL-WMR Graphic based (84)
74 EPP Entropy-based position projection (6)
75 CONSENSUS Greedy Algorithm (85)
76 By Huang et al heuristic algorithm (86)
GA
77 St-GA (87)
78 GAMI (88)
79 FMGA Simple GA (89)
80 MDGA (90)
81 By Paul et al (91)
82 By Vijayvargiya et al Clustering (92)
83 By Gutierrez et al (93)
84 GARPS (94)
85 GAEM (95)
86 GADEM (96)
87 CompareProspector (97)
88 By Fatemeh et al Hybrid (98)
89 GEMFA (99)
90 MRPGA (100)
91 By Xiaochun et al (101)
92 GAME (19)
93 By Yetian et al (102)
94 By Li et al Others (103)
95 MOGAMOD (104)
PSO
96 PMbPSO Standard PSO (4)
97 LPBS (105)
98   PSOMF (106)
99 Lei et al (107)
100 Lei et al (108)
101 DSAPSO Modified PSO (109)
102 By Karabulut et al (110)
103 Lei et al (111)
104 Hardin et al (112)
105 GSA-PSO Hybrid (113)
106 SPSO-Lk (114)
ABC algorithm
107 Multiobjective ABC (115)
108 MO-ABC/DE ABC (116)
109 Consensus ABC (8)
ACO algorithm
110 Machhi et al ACO with Gibbs sampling (117)
111 MFACO (118)
112 Cheng et al ACO with EM (119)
CS algorithm
113 MACS CS (120)
Combinatorial
114 STGEMS Enumerative and probalistic approaches (121)
115 MDScan (122)
116 MUSA Probabilstic and machine learning approaches (123)
117 EMD Multiple algorithms (124)
118 MobyDick Dictionary (125)
119 WordSpy (126)