Table 1.
Baseline clinical, laboratory, and angiographic characteristics
| Variable | fQRS(−), n = 619 | fQRS(+), n = 276 | P Value |
|---|---|---|---|
| Age, y | 57.5 ± 12.6 | 60.4 ± 13.8 | 0.002 |
| Male sex | 466 (75.3) | 211 (76.4) | 0.707 |
| BMI, kg/m2 | 28.2 ± 4.3 | 27.3 ± 4.3 | 0.016 |
| HTN | 235 (38.0) | 107 (38.8) | 0.819 |
| DM | 174 (28.1) | 75 (27.2) | 0.773 |
| Current smoker | 333 (53.8) | 155 (56.2) | 0.512 |
| Hypercholesterolemia | 158 (25.6) | 81 (29.3) | 0.374 |
| Family history of CAD | 188 (30.4) | 88 (31.9) | 0.651 |
| Prior CABG | 14 (2.3) | 9 (3.3) | 0.383 |
| SBP, mm Hg | 129 ± 23 | 125 ± 26 | 0.020 |
| DBP, mm Hg | 78 ± 14 | 77 ± 15 | 0.325 |
| Heart rate, bpm | 78 ± 15 | 81 ± 18 | 0.034 |
| Infarct location | 0.138 | ||
| Anterior | 265 (42.8) | 135 (48.9) | |
| Inferior | 298 (48.1) | 124 (44.9) | |
| Other (lateral, true posterior) | 56 (9.0) | 17 (6.2) | |
| LVEF, % | 47 ± 10 | 42 ± 10 | <0.001 |
| Killip class ≥2 on admission | 23 (3.7) | 32 (11.4) | <0.001 |
| Time from chest pain to primary PCI | 0.058 | ||
| 0–6 hours | 501 (80.9) | 208 (75.4) | |
| 6–12 hours | 118 (19.1) | 68 (24.6) | |
| Total ischemic time, min | 150 (120–240) | 180 (120–360) | 0.190 |
| WBC count, ×109/L | 11.5 ± 3.2 | 12.5 ± 4.0 | <0.001 |
| Platelet count, ×109/L | 245 ± 66 | 250 ± 75 | 0.321 |
| Hgb, g/dL | 14.3 ± 1.7 | 14.1 ± 1.9 | 0.140 |
| Glucose, mg/dL | 156 ± 79 | 152 ± 81 | 0.581 |
| Cr, mg/dL | 1.06 ± 0.24 | 1.12 ± 0.31 | 0.005 |
| GFR, mL/min/1.73 m2 | 75.5 ± 19.1 | 71.0 ± 21.2 | 0.002 |
| Peak CK‐MB, U/L | 61 (23–145) | 113 (54–227) | <0.001 |
| Peak TnT, ng/mL | 2300 (737–7312) | 4297 (1659–10000) | <0.001 |
| Total cholesterol, mg/dL | 192 ± 47 | 188 ± 45 | 0.293 |
| HDL‐C, mg/dL | 39 ± 8 | 40 ± 9 | 0.245 |
| LDL‐C, mg/dL | 123 ± 40 | 119 ± 40 | 0.287 |
| TG, mg/dL | 142 (94–204) | 137 (94–185) | 0.338 |
| hs‐CRP, mg/L | 7.21 (2.75–10.6) | 9.91 (3.32–14.6) | 0.001 |
| Initial IRA patency | 290 (46.8) | 69 (25.0) | <0.001 |
| Postprocedural no‐reflow phenomenon | 81 (13.1) | 78 (28.3) | <0.001 |
| Multivessel CAD | 308 (49.8) | 160 (58.0) | 0.023 |
| Presence of chronic total occlusion | 62 (10.0) | 44 (15.9) | 0.011 |
| SYNTAX score | 15.4 ± 8.3 | 19.7 ± 8.7 | <0.001 |
| ST‐segment resolution in ECG | 527 (85.2) | 121 (44.1) | <0.001 |
| Stent diameter, mm | 3.18 ± 0.45 | 3.21 ± 0.42 | 0.348 |
| Total stent length, mm | 25.3 ± 12.0 | 27.6 ± 12.6 | 0.011 |
| CIN | 14 (2.3) | 63 (22.8) | <0.001 |
| In‐hospital mortality | 2 (0.3) | 21 (7.6) | <0.001 |
Abbreviations: BMI, body mass index; CABG, coronary artery bypass surgery; CAD, coronary artery disease; CIN, contrast‐induced nephropathy; CK‐MB, creatine kinase–myocardial band; Cr, creatinine; DBP, diastolic blood pressure; DM, diabetes mellitus; ECG, electrocardiography; fQRS, fragmented QRS complex; GFR, glomerular filtration rate; HDL‐C, high‐density lipoprotein cholesterol; Hgb, hemoglobin; hs‐CRP, high‐sensitivity C‐reactive protein; HTN, hypertension; IQR, interquartile range; IRA, infarct‐related artery; LDL‐C, low‐density lipoprotein cholesterol; LVEF, left ventricular ejection fraction; PCI, percutaneous coronary intervention; SBP, systolic blood pressure; SD, standard deviation; TG, triglycerides; TnT, troponin T; WBC, white blood cell.
Data are presented as n (%), mean ± SD, or median (IQR).