Table 1.
Randomized Trials Comparing Provisional Strategy and Complex Strategy for Coronary Bifurcation Lesions
| Study Authors and Year | Comparison | Size | MACE % PS/CS | CV Death % PS/CS | MI % PS/CS | TVR % PS/CS | MV Restenosis % PS/CS | SB Restenosis % PS/CS |
|---|---|---|---|---|---|---|---|---|
| Colombo 200410 | CS vs PS | 85 | N/A | 0/1.6, P = NS | 9/11.1, P = NS | 9/11.1, P = NS | 4.8/5.7, P = NS | 14.2/21.8, P = NS |
| Pan 20049 | CS vs PS | 91 | 6.4/6.4 | 0/1.0 | 4/0 | 2/5 | 2/5 | 5/10 |
| NORDIC; Steigen 20061 | Crush, culotte, Y vs PS | 413 | 2.9/3.4 | 1.0/1.0, P = 1.00 | 0/0.5, P = 0.31 | 1.9/1.9, P = 0.99 | 4.6/5.1, P = 0.84 | 19.2/11.5, P = 0.062 |
| CACTUS; Colombo 20093 | Crush vs PS | 350 | 15.0/15.8, P = 0.95 | 0/0.5, P = 0.49 | 8.6/10.7, P = 0.59 | 7.5/7.9, P = 1.00 | 6.7/4.6, P > 0.05 | 14.7/13.2, P > 0.05 |
| BBK; Ferenc 200811 | T stenting vs PS | 202 | 12.9/11.9, P = 0.83 | 2.0/1.0, P = 1.00 | 1/2, P = 1.00 | N/A | 7.3/3.1, P = 0.17 | 9.4/12.5, P = 0.32 |
| Lin 201013 | DK crush, culotte, T vs PS | 108 | 11.1/38.9, P < 0.01 | 1.9/0, P = 1.00 | 1.9/1.9, P = 0.48 | 29.6/7.4, P < 0.01 | 14.8/9.3, P = 0.38 | 35.2/14.8, P = 0.015 |
| BBC‐ONE; Hildick‐Smith 20104 | Crush, culotte, T vs PS | 500 | 8.0/15.2, P = 0.009 | 0.4/0.8 | 3.6/11.2, P = 0.001 | 5.6/7.2, P = 0.43 | N/A | N/A |
| DKCRUSH II; Chen 200116 | DK crush vs PS | 390 | 17.3/10.3, P = 0.07 | 1.1/1.1, P = 1.00 | 2.2/3.2, P = 0.751 | 14.6/6.5, P = 0.017 | 9.7/3.8, P = 0.036 | 22.2/4.9, P < 0.001 |
| NORDIC Baltic IV; Kumsars 2013 | CS vs PS | 450 | 12.9/8.3, P = 0.12 | 0/0 | 1.8/0.9, P = 0.5 | 3.7/1.3, P = 0.11 | 2.6/2, P = NS | 20.3/5.2, P < 0.001 |
| PERFECT; Kim 201512 | Crush vs PS | 419 | 18.5/17.8, P = 0.85 | 0.5/0.9 P = 0.58 | 14.1/14.1, P = 0.98 | 3.4/2.9, P = 0.73 | 4.8/5.2, P = 0.90 | 8.3/3.9, P = 0.12 |
Abbreviations: BBC‐ONE, British Bifurcation Coronary Study: Old, New and Evolving Strategies; BBK, Bifurcations Bad Krozingen; CACTUS, Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus‐Eluting Stents; CS, complex strategy; CV, cardiovascular; DK, double kissing; DKCRUSH, Double Kissing Crush vs Provisional Stenting Technique for Treatment of Coronary Bifurcation Lesions; MACE, major adverse cardiovascular events; MI, myocardial infarction; MV, main vessel; NORDIC, Nordic Bifurcation Stent Technique Study; NS, not significant; PERFECT, Optimal Stenting Strategy for True Bifurcation Lesions; PS, provisional strategy; SB, side branch; TVR, target‐vessel revascularization.