Figure 1.
Oxidative stress in atherogenesis: role of tocopherols. Postulated steps in atherogenesis. *Steps at which the tocopherols act to decrease oxidative stress. They decrease SMC proliferation, decrease platelet aggregation, increase NO availability, decrease endothelial dysfunction, and decrease lipid peroxidation. Abbreviations: LDL, low‐density lipoprotein; NO, nitric oxide; Ox‐LDL, oxidized low‐density lipoprotein; RNS, reactive nitrogen species; ROS, reactive oxygen species; SMC, smooth muscle cell.