Table 3.
Relationships of the number of classes of medications prescribed with long‐term outcomes, compared with patients using no anginal medications
| Mortality | MI | Mortality or MI | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Event Rate1 | Unadjusted HR (95% CI) | Adjusted HR (95% CI) | Event Rate2 | Unadjusted HR (95% CI) | Adjusted HR (95% CI) | Event Rate1 | Unadjusted HR (95% CI) | Adjusted HR (95% CI) | |
| Any vs 0 | 25 vs 27 | 0.94 (0.80‐1.11) | 0.75 (0.63‐0.89) | 7 vs 4 | 1.68 (1.11‐2.53) | 1.52 (1.00‐2.30) | 29 vs 30 | 1.02 (0.87‐1.20) | 0.83 (0.71‐0.98) |
| 1 class vs 0 | 21 vs 27 | 0.78 (0.65‐0.93) | 0.65 (0.54‐0.78) | 6 vs 4 | 1.47 (0.95‐2.27) | 1.42 (0.92‐2.20) | 26 vs 30 | 0.86 (0.73‐1.02) | 0.74 (0.62‐0.88) |
| 2 classes vs 0 | 25 vs 27 | 0.95 (0.80‐1.14) | 0.77 (0.64‐0.92 | 7 vs 4 | 1.75 (1.14‐2.70) | 1.57 (1.02‐2.43) | 30 vs 30 | 1.04 (0.88‐1.24) | 0.86 (0.72‐1.02) |
| 3 or 4 classes vs 0 | 34 vs 27 | 1.37 (1.13‐1.67) | 0.96 (0.79‐1.18) | 8 vs 4 | 2.06 (1.29‐3.29) | 1.65 (1.03‐2.66) | 38 vs 30 | 1.42 (1.18‐1.71) | 1.03 (0.85‐1.24) |
Abbreviations: CI, confidence interval; HR, hazard ratio; MI, myocardial infarction.
1
5‐year unadjusted Kaplan‐Meier event rate (%).
2
5‐year unadjusted cumulative incidence rate (%).