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. 2019 Apr 30;14(4):e0215911. doi: 10.1371/journal.pone.0215911

Table 1. Putative eSNPs in LD with trait-associated GWAS SNPs.

Chr eSNP GWAS SNP r2 Trait(s) p-value Reported Causal Gene(s) Nearest Gene(s) Reference(s)
1 rs17315646 rs10489615 0.97 HDL 4x10-9 GALNT2 GALNT2 [6]
rs2144300 1 HDL 3x10-14 [2]
TG 8x10-7 [2]
rs4846914 1 HDL 2x10-13 [1],[4]
TG 7x10-15 [1]
9 rs2575875 rs4149268 0.96 HDL 1x10-10 ABCA1 ABCA1 [2]
9
rs3847301
rs3890182 0.81 HDL 3x10-10 ABCA1 ABCA1 [1],[6]
rs3905000 0.81 HDL 9x10-13 [3]
9 rs643531 rs643531 1 HDL 7x10-9 TTC39B TTC39B [6]
11 rs12287066 rs12272004 0.83 TC 7x10-7 APOA1-C3-A4-A5 APOA5 [3]
LDL 5x10-13 [3]
TG 5x10-13 [3]
rs12286037 1 TG 1x10-26 [2]
rs28927680 1 TG 2x10-17 [1]
16 rs1109166 rs12449157 0.94 HDL 2x10-7 GFOD2, LCAT LCAT, SLC12A4 [6]
19 rs2075650 rs2075650 1 TC 3x10-19 TOMM4, APOE TOMM4, APOE [3]

r2 is based on HapMap CEU.p-values from the original GWAS studies.