Fig 3. Expression analysis of the miR-29b target genes COL1A2 and IGF1 from ADAR2-KO mouse hearts in three different biological replicates.

COL1A2 and IGF1 are cardiac hypertrophy and fibrosis related miR-29b target genes. miR-29b has been found downregulated ~2.0 fold in the absence of ADAR2. Bar graph showing slight but not significant changes in the expression of these genes. The error bars indicate the mean +/-SD. *P < 0.05 (versus control), as determined by the Mann–Whitney U test.