| Methods |
Country: Japan
Setting: hospital outpatient clinic
RCT |
| Participants |
Fifty children with mild atopic eczema/dermatitis syndrome and 25 normal children whose parents smoked 10 to 15 CPD at home |
| Interventions |
Intervention: not clear: “Parents of the cessation of passive smoking group agreed to stop smoking”
Control: usual care |
| Outcomes |
At 1 month:
• Child urinary cotinine
• Child skin wheal response
• Child plasma neurotrophin levels |
| Type of intervention |
Child with health problems (ill‐child health care) |
| Notes |
Not provided |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
"Randomly divided"; no further information provided |
| Allocation concealment (selection bias) |
Unclear risk |
Not described |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
No information provided |
| Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
Biochemical validation used |
