Antipsychotic cessation compared with antipsychotic maintenance for antipsychotic‐induced tardive dyskinesia |
Patient or population: psychiatric patients with antipsychotic‐induced tardive dyskinesia
Setting: inpatients and outpatients in any country
Intervention: Antipsychotic cessation
Comparison: Antipsychotic maintenance |
Outcomes |
Illustrative comparative risks* (95% CI) |
Relative effect
(95% CI) |
No of participants
(studies) |
Quality of the evidence
(GRADE) |
Comments |
Assumed risk |
Corresponding risk |
Antipsychotic maintenance |
Antipsychotic cessation |
There is no evidence about the effects of withdrawal of antipsychotics compared with continuation of antipsychotics; none of the included studies evaluated this comparison. |
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*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval |
GRADE Working Group grades of evidence
High quality: we are very confident that the true effect lies close to that of the estimate of the effect
Moderate quality: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low quality: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect
Very low quality: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect |