Jafarabadi 2016.
| Methods | Parallel group study Number of women randomised: 266 (133 in the intervention group; 133 in the control group) Number of cancellations: 3 women in the intervention group did not receive the intervention Number of women analysed: 263 |
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| Participants | Country of authors: Iran Inclusion criteria: couples undergoing assisted reproduction with a female partner < 40 years of age Exclusion criteria: history of no oocytes in a former ART cycle, > 2 prior ART cycles, providing semen by any other means than ejaculation, active hepatitis B, or C or HIV in one partner, leukocytospermia Mean age ± SD: intervention group: 32.2 ± 6.0 years; control group: 31.1 ± 6.0 years. Mean duration of infertility ± SD: not reported. Women with primary infertility: not reported. Setting: assisted reproduction programme in Iran |
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| Interventions | Intervention: intracervical injection of 0.5 ml seminal plasma was after the oocyte pick‐up procedure. The rest of the available seminal plasma was deposited at the posterior vaginal fornix. Control: no intervention |
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| Outcomes | Clinical pregnancy defined as visualisation of embryo by ultrasound at sixth gestational week | |
| Notes | We tried to contact the authors by email, twice one month apart, however did not receive a response | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Permuted block randomisation |
| Allocation concealment (selection bias) | Unclear risk | Not reported |
| Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Embryologist not blinded for allocation |
| Blinding of outcome assessment (detection bias) All outcomes | Low risk | Objectively measured outcome |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Three women in the intervention group were unaccounted for in the analyses |
| Selective reporting (reporting bias) | Unclear risk | Several outcome measures that should be available to the authors were not reported, e.g. multiple pregnancy rate, miscarriage rate |
| Other bias | Unclear risk | Poor reporting quality |