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. 2018 Feb 1;2018(2):CD004876. doi: 10.1002/14651858.CD004876.pub4

Comparison 13. Influenza vaccines with adjuvant versus no vaccination: cohort studies in community‐dwellers.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
13.1 Influenza‐like illness 2 498 Risk Ratio (M‐H, Random, 95% CI) 0.30 [0.16, 0.56]
13.1.1 Epidemic year ‐ vaccine matching 1 263 Risk Ratio (M‐H, Random, 95% CI) 0.20 [0.07, 0.54]
13.1.2 Epidemic year ‐ vaccine matching absent or unknown 0 0 Risk Ratio (M‐H, Random, 95% CI) Not estimable
13.1.3 Non‐epidemic year ‐ vaccine matching 1 235 Risk Ratio (M‐H, Random, 95% CI) 0.38 [0.18, 0.82]
13.2 Hospitalisation for influenza or pneumonia or respiratory disease 2 498 Risk Ratio (M‐H, Random, 95% CI) 0.17 [0.02, 1.28]
13.2.1 Epidemic year ‐ vaccine matching 0 0 Risk Ratio (M‐H, Random, 95% CI) Not estimable
13.2.2 Epidemic year ‐ vaccine matching absent or unknown 0 0 Risk Ratio (M‐H, Random, 95% CI) Not estimable
13.2.3 Non‐epidemic year ‐ vaccine matching 2 498 Risk Ratio (M‐H, Random, 95% CI) 0.17 [0.02, 1.28]
13.3 All deaths 1 235 Risk Ratio (M‐H, Random, 95% CI) 2.10 [0.10, 43.10]
13.3.1 Epidemic year ‐ vaccine matching 0 0 Risk Ratio (M‐H, Random, 95% CI) Not estimable
13.3.2 Epidemic year ‐ vaccine matching absent or unknown 0 0 Risk Ratio (M‐H, Random, 95% CI) Not estimable
13.3.3 Non‐epidemic year ‐ vaccine matching 1 235 Risk Ratio (M‐H, Random, 95% CI) 2.10 [0.10, 43.10]