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. 2018 Feb 1;2018(2):CD004876. doi: 10.1002/14651858.CD004876.pub4

Comparison 14. Influenza vaccines versus no vaccination: case‐control studies in community.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
14.1 Hospitalisations for influenza or pneumonia 2 1074 Odds Ratio (M‐H, Random, 95% CI) 0.89 [0.69, 1.15]
14.1.1 Outbreak ‐ vaccine matching (circulating strains) 0 0 Odds Ratio (M‐H, Random, 95% CI) Not estimable
14.1.2 Outbreak ‐ vaccine matching absent or unknown 1 825 Odds Ratio (M‐H, Random, 95% CI) 0.92 [0.69, 1.22]
14.1.3 No outbreak ‐ vaccine matching 1 249 Odds Ratio (M‐H, Random, 95% CI) 0.82 [0.48, 1.40]
14.2 Hospitalisations for any respiratory disease 4 21378 Odds Ratio (M‐H, Random, 95% CI) 1.08 [0.95, 1.23]
14.2.1 Outbreak ‐ vaccine matching 3 20582 Odds Ratio (M‐H, Random, 95% CI) 1.08 [0.92, 1.26]
14.2.2 No outbreak ‐ not matching 1 796 Odds Ratio (M‐H, Random, 95% CI) 1.02 [0.68, 1.52]
14.3 Deaths from influenza or pneumonia 1 1092 Odds Ratio (M‐H, Random, 95% CI) 0.74 [0.53, 1.04]
14.3.1 Outbreak ‐ vaccine matching 1 1092 Odds Ratio (M‐H, Random, 95% CI) 0.74 [0.53, 1.04]
14.4 Pneumonia (no better defined) 1 519 Odds Ratio (M‐H, Fixed, 95% CI) 0.87 [0.57, 1.33]
14.4.1 Outbreak ‐ partially matching 1 519 Odds Ratio (M‐H, Fixed, 95% CI) 0.87 [0.57, 1.33]