| Study characteristics |
| Methods |
Authors investigated an outbreak in a nursing home, in Columbia, UK, during the 1982 to 1983 influenza season; active surveillance by home staff. Follow‐up period was 31 January 1983 to 25 February 1983. Pharyngeal swab and paired sera were collected to confirm diagnosis from 13 and 32 participants, respectively. |
| Participants |
116 nursing home residents (26 treated and 90 controls, all included in the analysis) with underlying illnesses, 30 to 108 years old (mean age 71 years) |
| Interventions |
Parenteral influenza vaccine: A/Brazil/11/78; A/Bangkok/1/79; B/Singapore/79. Vaccine strains did not match circulating strains. |
| Outcomes |
ILI (any acute respiratory tract infection occurring during outbreak, with or without fever), pneumonia, death from respiratory disease |
| Notes |
10 participants were given amantadine, not indicated if vaccinees or unvaccinated. The circulating strain was related to A/Philippines/2/82. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Unclear risk |
B ‐ Unclear |
