Study characteristics |
Methods |
Authors investigated an outbreak in a skilled care nursing home, in Connecticut, USA, during the 1984 to 1985 influenza season; medical records were reviewed. Follow‐up period was 1 December 1984 to 15 January 1985. Paired sera specimens were obtained from some ill residents. |
Participants |
131 residents (96 treated and 48 controls, 96 and 35 included in the analysis respectively), 65 to 95 years old |
Interventions |
Parenteral influenza vaccine: A/Philippines/2/82; A/Chile/83; B/USSR/100/82. Vaccine strains probably matched circulating strains. |
Outcomes |
Clinically defined ILI (fever 37.8 °C or greater, cough, coryza, sore throat); hospitalisation from ILI; deaths occurring within 2 weeks of ILI with no other explanation |
Notes |
Amantadine was not used. There was serological evidence of A(H3N2) influenza infections. |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Allocation concealment (selection bias) |
Unclear risk |
B ‐ Unclear |