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. 2018 Feb 1;2018(2):CD004876. doi: 10.1002/14651858.CD004876.pub4

Isaacs 1997.

Study characteristics
Methods Authors investigated an outbreak in a nursing home in Ontario, Canada during the 1996 to 1997 influenza season. Follow‐up period was 1 January 1997 to 11 January 1997. Nasal swabs were obtained from 3 ill residents.
Participants 172 nursing home residents (149 treated and 23 controls, all included in the analysis)
Interventions Parenteral influenza vaccine. Vaccine strains probably matched circulating strains (other studies).
Outcomes Clinically defined ILI (fever 38 °C or greater, cough, sore throat, nasal congestion, muscle ache, lethargy, lasting 2 days or more)
Notes Amantadine was used in all residents. 1 positive result was obtained by rapid testing. Poor reporting
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) High risk C ‐ Inadequate